Tuesday, November 10, 2015

Animal testing is a cruel and un-ethnical because it is not needed in science today.


95% of animals used in experiments are NOT protected by the Animal Welfare Act and “over 100 million animals are burned, crippled, poisoned, and abused” every year in United States labs alone!  More info.  Not only that, but several of the tests performed draw inaccurate or inconclusive results because of the simple fact that animals are not human.  Regulations.  Innumerable animal lives are lost, and the process often fails to predict human responses because traditional animal models do not accurately mimic human physiology.


Attempting to duplicate human diseases, and data derived from physiologically altered animals due to unavoidable stress in the laboratory environment raises complications in the interpretation of the results.  Trapped, confined, and constantly under stress, these animals are hardly in any mental state to produce accurate, reliable results.

The law doesn’t require many of these tests to be performed and they often produce misleading and inaccurate results.  While their organs may be similar in their DNA and function, their bodies will handle human diseases injected in them differently and in different proportions.

Documents have shown that “species differences in liver detoxification capacity may explain why many drugs are safe in animals, despite the fact that liver toxicity is the major reason for drug relabeling and withdrawal in humans.” (FDA conference study documents, May 24, 2001.)  A “synthetic combination of chemicals that mimics a liver” has been developed by scientists and put to the test, concluding that the “stand-in liver may be used to test drugs for metabolic toxicity” among other things. (Animal Testing, Wiki)

Scientists and engineers at Harvard's Wyss Institute have put their ideas and new technology together, creating small devices that contain human cells that mimic human organs.  These include:
  •  "organs-on-a-chip"
  • "lung-on-a-chip"
  • "gut-on-a-chip"

The chips can be used—instead of animals in in vitro disease research, drug testing, and toxicity testing.  3-D bioprinters have also been used to create human cells for in vitro testing.”  If put into worldwide use, these tiny devices will solve many of the problems posed from testing on animals as well as the ethnicity of doing so.  These "organs-on-a-chip" have been tested and proven to:
  • Provide an accurate alternative to animal tests that often fail to predict human responses
  • Test the effects of new drug candidates for safety and efficacy in human tissues
  • Test the safety of cosmetics
  • Test the toxicity of chemicals
  • Help scientists elucidate how tissues respond to new drug candidates
  • Ensure more accurate conclusions from the results

More organs-on-a-chip information here.

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